The science

Built on clinical research and disclosed doses.

Published research on named ingredients, with doses on the label. Here are the six pathways the 13-ingredient Oral Blend is built around, and how the nine-active Liquid Halo™ scalp serum (coming soon) complements it. Zero proprietary blends.

Shop the Oral Blend Ingredient glossary
The proof, cited

What the research on each ingredient reported

Every line below is a published study of a named ingredient, with its type and size. Each links to its source.

  1. SEREVELLE®

    People taking the ingredient gained +18.6 terminal hairs in the target area, versus −10.1 on placebo.

    180-day randomized, double-blind, placebo-controlled study · 60 adults · 160 mg/day stand-alone softgel (FLOTE provides 295 mg; finished formula not clinically tested) · Ablon 2026, J Cosmet Dermatol ↗
  2. KSM-66®

    At 250 mg/day (125 mg twice daily), improved perceived stress and serum cortisol versus placebo in stressed, otherwise healthy adults.

    8-week randomized, placebo-controlled study · did not test hair outcomes · Salve 2019, Cureus ↗
  3. AnaGain™ Nu

    At 100 mg/day, mean collected comb/brush hair counts fell from 163.7 to 105.7 by day 28 (−33.9%) and to 100.4 at eight weeks.

    8-week oral pilot · 21 completers · no control group, preliminary evidence · AnaGain Nu oral pilot ↗
  4. Ferrochel®

    Iron supports hemoglobin and oxygen transport and normal cellular function.

    Established nutrient physiology (reference) · NIH iron fact sheet ↗

These are ingredient studies, not finished-product results. The FLOTE RADIANCE Oral Blend has not completed a clinical trial of its own, and individual results vary.

Why it works

Six pathways. One system.

Each pathway, the ingredient behind it, and the research we can show you.

  1. In a 180-day randomized, placebo-controlled study of the ingredient (Ablon 2026, PMID 41652806), adults taking SEREVELLE® gained +18.6 terminal hairs in the target area versus −10.1 on placebo. The study used 160 mg/day; FLOTE provides 295 mg. A study of the ingredient, not of the finished formula.

    • SEREVELLE® saw palmetto295 mg
    See the science

  2. In an eight-week randomized, placebo-controlled study, 250 mg/day of KSM-66® (125 mg twice daily) improved perceived stress and serum cortisol versus placebo (Salve 2019, PMID 32021735). The study did not measure hair.

    • KSM-66® ashwagandha250 mg
    • Mucuna pruriens187 mg
    See the science

  3. Iron is part of hemoglobin, which carries oxygen in the blood. Ferrochel® is iron bound to glycine with Balchem's TRAACS® chelation technology. Ginkgo is included as a complementary botanical.

    • Ferrochel® iron25 mg
    • Ginkgo biloba157 mg
    See the science

  4. In a published eight-week oral pilot at 100 mg/day, mean collected comb/brush hair counts fell from 163.7 to 105.7 by day 28 (−33.9%). 21 completers, no control group: early evidence.

    • AnaGain™ Nu100 mg
    • Gotu kola220 mg
    See the science

  5. Zinc supports protein synthesis and cell division, biotin is a cofactor for normal hair maintenance, selenium supports antioxidant defense and niacinamide normal energy metabolism.

    • Zinc20 mg
    • Selenium100 mcg
    • Biotin5,000 mcg
    • Niacinamide16 mg
    • Moringa150 mg
    • Triphala150 mg
    See the science

  6. Liquid Halo™ works at the scalp at night: nine actives across five complementary mechanisms, 17.5% combined. Coming soon.

    • Liquid Halo™ scalp serum, 9 actives at 17.5%
    See the science
Pathway 1 of 6

Follicle defense

In a 180-day randomized, placebo-controlled study of the ingredient (Ablon 2026, PMID 41652806), adults taking SEREVELLE® gained +18.6 terminal hairs in the target area versus −10.1 on placebo. The study used 160 mg/day; FLOTE provides 295 mg. A study of the ingredient, not of the finished formula.

See the science
In the formula
  • SEREVELLE® saw palmetto295 mg

+18.6 terminal hairs (180-day study)

Pathway 2 of 6

Stress balance

In an eight-week randomized, placebo-controlled study, 250 mg/day of KSM-66® (125 mg twice daily) improved perceived stress and serum cortisol versus placebo (Salve 2019, PMID 32021735). The study did not measure hair.

See the science
In the formula
  • KSM-66® ashwagandha250 mg
  • Mucuna pruriens187 mg

Lower stress & cortisol in 8 weeks

Pathway 3 of 6

Oxygen supply

Iron is part of hemoglobin, which carries oxygen in the blood. Ferrochel® is iron bound to glycine with Balchem's TRAACS® chelation technology. Ginkgo is included as a complementary botanical.

See the science
In the formula
  • Ferrochel® iron25 mg
  • Ginkgo biloba157 mg

Supports normal oxygen transport

Pathway 4 of 6

Hair cycle

In a published eight-week oral pilot at 100 mg/day, mean collected comb/brush hair counts fell from 163.7 to 105.7 by day 28 (−33.9%). 21 completers, no control group: early evidence.

See the science
In the formula
  • AnaGain™ Nu100 mg
  • Gotu kola220 mg

−33.9% shed hairs by day 28 (pilot)

Pathway 5 of 6

Nutrition

Zinc supports protein synthesis and cell division, biotin is a cofactor for normal hair maintenance, selenium supports antioxidant defense and niacinamide normal energy metabolism.

See the science
In the formula
  • Zinc20 mg
  • Selenium100 mcg
  • Biotin5,000 mcg
  • Niacinamide16 mg
  • Moringa150 mg
  • Triphala150 mg

Cofactors for normal hair

Pathway 6 of 6

Topical precision

Liquid Halo™ works at the scalp at night: nine actives across five complementary mechanisms, 17.5% combined. Coming soon.

See the science
In the formula
  • Liquid Halo™ scalp serum, 9 actives at 17.5%

9 actives, 5 mechanisms (coming soon)

Published studies evaluate named ingredients, not the complete FLOTE RADIANCE formula. Individual results vary. “Complementary” describes how the formula is built. The complete combination has not been clinically tested for additive or synergistic effects.

Four named technologies

Four named technologies. Each dosed and sourced.

Three with published human ingredient research; Ferrochel® for established iron physiology. The research is on the ingredients, not on the finished FLOTE formula, and individual results vary.

SEREVELLE®
295 mg
Valensa International · Eustis, Florida

Saw palmetto supercritical CO₂ extract: the formula’s primary hair-focused botanical.

60 adults, 180 days, placebo-controlled: +18.6 terminal hairs vs −10.1 on placebo (ingredient at 160 mg/day).

Read more ↓
KSM-66®
250 mg
Ixoreal Biomed · Hyderabad, India

Ashwagandha root extract, standardized to 5% withanolides: healthy stress-response support.

8 weeks, randomized and placebo-controlled, at 250 mg/day: improved perceived stress and serum cortisol vs placebo.

Read more ↓
AnaGain™ Nu
100 mg
Mibelle Biochemistry · Buchs, Switzerland

Organic pea-sprout extract: hair-cycle and shedding support.

Published 8-week oral pilot at 100 mg/day: mean collected hair counts fell from 163.7 to 105.7 by day 28 (−33.9%).

Read more ↓
Ferrochel® iron
TRAACS®
25 mg
Balchem Corporation · New Hampton, New York

Iron bound to glycine with Balchem's TRAACS® chelation technology: iron for oxygen transport.

Iron supports hemoglobin and oxygen transport and normal cellular function.

Read more ↓
SEREVELLE® · 295 mg

Why the extract matters

SEREVELLE® is a supercritical CO₂ saw palmetto extract from Valensa International in Eustis, Florida. FLOTE provides 295 mg per day.

The research

In a 180-day randomized, double-blind, placebo-controlled study of 60 adults with self-perceived thinning, people taking the ingredient gained +18.6 terminal hairs in the target area, versus −10.1 on placebo. The study used 160 mg/day as a stand-alone softgel; FLOTE provides 295 mg, and the finished formula has not been clinically tested.

Ablon 2026, J Cosmet Dermatol ↗
What it is not. A study of the ingredient, not of the FLOTE formula. It does not show that any finished product will produce the same result.
KSM-66® · 250 mg

A clinically researched adaptogen

KSM-66® is a full-spectrum root extract standardized to 5% withanolides, from organic roots. It supports a healthy stress response.

The research

In an eight-week randomized, placebo-controlled study of stressed, otherwise healthy adults, 250 mg/day (125 mg twice daily) improved perceived stress and serum cortisol versus placebo. The study did not test hair outcomes.

Salve 2019, Cureus ↗
What it is not. The study did not test hair outcomes.
AnaGain™ Nu · 100 mg

Early evidence at the follicle

AnaGain™ Nu is an organic pea-sprout extract from Mibelle Biochemistry, studied at the same 100 mg daily amount in a published eight-week oral pilot.

The research

Mean collected comb/brush hair counts fell from 163.7 to 105.7 by day 28 (−33.9%) and to 100.4 at eight weeks. 21 completers, no control group.

AnaGain Nu oral pilot ↗
What it is not. Preliminary ingredient evidence only: a small pilot with no control group.
Ferrochel® iron · 25 mg

Iron needs are individual

Iron supports hemoglobin and oxygen transport and normal cellular function. Ferrochel® is iron bound to glycine with Balchem's TRAACS® chelation technology. Iron needs are individual, so more is not automatically better.

The research

Iron’s role in hemoglobin, oxygen transport and normal cellular function is established nutrient physiology; see the NIH iron fact sheet.

NIH iron fact sheet ↗
What it is not. A nutrient, not a hair claim. Iron needs are individual, so more is not automatically better.
Clinical evidence

The evidence table

Every named active in the system, its disclosed dose, and exactly what kind of evidence stands behind it: 5 peer-reviewed, journal-published studies and 5 supplier-generated clinical or in vitro dossiers. We label each one rather than blur the difference.

ActiveFormula & doseEvidence typeKey study
SEREVELLE® saw palmetto
295 mg oral + 2.0% topical
Peer-reviewed study

In a 180-day randomized, double-blind, placebo-controlled study of 60 adults with self-perceived thinning, people taking the ingredient gained +18.6 terminal hairs in the target area, versus −10.1 on placebo. The study used 160 mg/day as a stand-alone softgel; FLOTE provides 295 mg, and the finished formula has not been clinically tested.

Ablon G. “The Safety and Efficacy of a Novel Saw Palmetto (Serenoa repens) Extract for Promoting Hair Growth in Adults With Self-Perceived Thinning Hair: 180-Day Results.” J Cosmet Dermatol. 2026;25(2):e70717. PMID: 41652806.
KSM-66® Ashwagandha
250 mg oral (5% withanolides)
Peer-reviewed study

In an eight-week randomized, placebo-controlled study of stressed, otherwise healthy adults, 250 mg/day (125 mg twice daily) improved perceived stress and serum cortisol versus placebo. The study did not test hair outcomes. Full-spectrum root extract standardized to 5% withanolides.

Salve J, et al. Cureus. 2019;11(12):e6466. PMID: 32021735.
AnaGain™ Nu
100 mg oral + 3.0% topical
Peer-reviewed study

In a published eight-week oral pilot at 100 mg/day, mean collected comb/brush hair counts fell from 163.7 to 105.7 by day 28 (−33.9%) and to 100.4 at eight weeks. 21 completers, no control group: preliminary ingredient evidence.

Grothe T, Wandrey F, Schuerch C. “Short communication: Clinical evaluation of pea sprout extract in the treatment of hair loss.” Phytother Res. 2020;34(2):428–431.
Ferrochel® iron
25 mg oral (139% DV)
Peer-reviewed study

Iron supports hemoglobin and oxygen transport and normal cellular function. Ferrochel® is iron bound to glycine with Balchem's TRAACS® chelation technology. Iron needs are individual, so more is not automatically better. The cited trial is a pregnancy iron-status study of ferrous bisglycinate, not a hair study.

Milman N, Jønsson L, Dyre P, Pedersen PL, Larsen LG. “Ferrous bisglycinate 25 mg iron is as effective as ferrous sulfate 50 mg iron in the prophylaxis of iron deficiency and anemia during pregnancy in a randomized trial.” J Perinat Med. 2014;42(2):197–206. PMID: 24152889.
Redensyl®
3.0% topical
Supplier clinical data
ETERWELL™ HAIR
0.5% topical
Supplier clinical data
BeauPlex® VH
1.0% topical
Supplier clinical data
COLHIBIN® CB
1.0% topical
Supplier clinical data
Bond Aid® + OXY-229 CB
1.0% topical
Supplier clinical data
GHK-Cu Copper Tripeptide
1.0% topical
Peer-reviewed study

GHK-Cu copper tripeptide is patented rather than trademarked and is held to the same disclosure standard as every other active in the Liquid Halo™ serum. Some studies above test a different dose than the amount disclosed in our formula; the amounts in the Formula & dose column are FLOTE RADIANCE’s own disclosed doses, not necessarily the exact dose used in the cited research. Individual results vary. This information is for educational purposes and is not intended to diagnose, treat, cure, or prevent any disease.

SEREVELLE® is a trademark of Valensa International. KSM-66® is a trademark of Ixoreal Biomed. AnaGain™ is a trademark of Mibelle Biochemistry. Ferrochel® and TRAACS® are trademarks of Albion Laboratories / Balchem. Redensyl® is a trademark of Givaudan. ETERWELL™ HAIR, BeauPlex® VH, COLHIBIN®, Bond Aid® and OXY-229 CB are trademarks of dsm-firmenich. Third-party marks belong to their respective owners.

The FLOTE difference

The category sells fog. We sell receipts.

See how FLOTE RADIANCE stacks up against the leading competitor.

FeatureFLOTE RADIANCELeading competitor
Lead hair-focused ingredient
✓SEREVELLE® supercritical CO₂ saw palmetto extract, 295 mg per day
✗Generic saw palmetto extract
Named ingredients
✓13 of 13 disclosed
✗Proprietary blend
Named technologies
✓SEREVELLE®, AnaGain™ Nu, KSM-66® and Ferrochel® in a 13-ingredient oral formula; 9-active Liquid Halo™ (coming soon)
✗1 proprietary complex
Formula transparency
✓Dose of each ingredient listed
✗Proprietary blend (hidden)
Unisex formula
✓Yes, one formula for all
✗No, separate SKUs
Topical serum system
✓Liquid Halo™ (coming soon): 9 actives from 5 named suppliers
✗Not included
Daily capsule burden
✓3 capsules
✗4 capsules
Money-back guarantee
✓180 days, first order, keep opened bottles
✗Unknown

Clinical figures describe the named ingredients, not the finished product. Individual results vary.

The complete system

Inside out, outside in. One ritual across a full hair cycle.

The Oral Blend by day: three capsules once daily with a meal and water. Liquid Halo™ at night, on the scalp (coming soon).

FLOTE RADIANCE Oral Blend
By day · Oral
Oral Blend

Three capsules once daily with a meal and water. Thirteen ingredients, each with a role.

Shop the Oral Blend
Liquid Halo scalp serum
At night · On the scalp · Coming soon
Liquid Halo™

Used at night, on the scalp: nine actives across five complementary mechanisms, 17.5% combined. Oral Blend by day, Liquid Halo™ at night: complementary parts of one ritual; combined use has not been clinically evaluated.

Designed as complementary parts of one ritual; combined use has not been clinically evaluated.

Questions

Evidence, explained

What does “clinically researched” mean here?+

Three of the 13 oral ingredients (SEREVELLE®, AnaGain™ Nu and KSM-66®) have published human ingredient research; Ferrochel® is included for established iron physiology. The rest are named and dosed on the label without a claim of their own clinical trial. FLOTE RADIANCE pairs the 13-ingredient Oral Blend with the nine-active Liquid Halo™ scalp serum (coming soon), including patented GHK-Cu copper tripeptide. Designed as complementary parts of one ritual; combined use has not been clinically evaluated.

What is SEREVELLE®?+

SEREVELLE® is a supercritical CO₂ saw palmetto extract from Valensa International in Eustis, Florida. FLOTE provides 295 mg per day.

Is there published research behind these ingredients?+

5 of the 10 actives in the evidence table (SEREVELLE®, KSM-66®, AnaGain™ Nu, Ferrochel®, and GHK-Cu) have been studied in peer-reviewed, journal-published research. The remaining 5 (Redensyl®, ETERWELL™ HAIR, BeauPlex® VH, COLHIBIN® CB, and Bond Aid® + OXY-229 CB) are supported by supplier-generated clinical or in vitro data that hasn’t been published in an independent, peer-reviewed journal. We label each row by its actual evidence type.

Does a published study mean FLOTE RADIANCE itself was tested?+

No. Every citation tests the named ingredient, often at a specific dose, from a specific supplier, not the finished FLOTE RADIANCE formula, and some published doses differ from the amount disclosed in our formula. We still cite the ingredient-level research because it’s the best available evidence for that active, but we’re not claiming our finished product was the subject of the clinical trial.

What is “supplier clinical data,” and why do you use it?+

Some of our ingredients are new enough, or specialized enough, that no independent peer-reviewed study exists yet. In those cases the only testing available is the manufacturer’s own in vitro or in vivo data. We disclose this openly and label it “Supplier clinical data” rather than presenting it as independent science.

Sources

References

  1. 01 Peer-reviewed study
    Ablon G. “The Safety and Efficacy of a Novel Saw Palmetto (Serenoa repens) Extract for Promoting Hair Growth in Adults With Self-Perceived Thinning Hair: 180-Day Results.” J Cosmet Dermatol. 2026;25(2):e70717. PMID: 41652806.
  2. 02 Peer-reviewed study
    Salve J, et al. Cureus. 2019;11(12):e6466. PMID: 32021735.
  3. 03 Peer-reviewed study
    Grothe T, Wandrey F, Schuerch C. “Short communication: Clinical evaluation of pea sprout extract in the treatment of hair loss.” Phytother Res. 2020;34(2):428–431.
  4. 04 Peer-reviewed study
    Milman N, Jønsson L, Dyre P, Pedersen PL, Larsen LG. “Ferrous bisglycinate 25 mg iron is as effective as ferrous sulfate 50 mg iron in the prophylaxis of iron deficiency and anemia during pregnancy in a randomized trial.” J Perinat Med. 2014;42(2):197–206. PMID: 24152889.
  5. 05 Supplier clinical data
    Chajra H, Lefevre F, Auriol D. “Native Polyphenols to Kick-start Hair Regrowth.” Cosmetics & Toiletries. 2017;132(6):24–35.
  6. 06 Supplier clinical data
    DSM-Firmenich in-house technical data: ETERWELL™ HAIR product dossier and SEPAWA Congress 2025 presentation.
  7. 07 Supplier clinical data
    DSM-Firmenich in-house clinical dossier: randomized, double-blind, placebo-controlled in vivo study, 60 volunteers, 5-month daily use (unpublished).
  8. 08 Supplier clinical data
    DSM-Firmenich Colhibin CB technical dossier: in vitro MMP-1 (collagenase) inhibition data (unpublished).
  9. 09 Supplier clinical data
    DSM-Firmenich, “dsm-firmenich Unveils Bond Aid with OXY 229 CB” (2025): in-house technical and press dossier.
  10. 10 Peer-reviewed study
    Uno H, Kurata S. “Chemical agents and peptides affect hair growth.” J Invest Dermatol. 1993;101(1 Suppl):143S–147S. PMID: 8326148.

FLOTE RADIANCE is a cosmetic and nutritional supplement system, not a drug, and is not intended to diagnose, treat, cure, or prevent any disease. Individual results vary.

Read before use

Premium also means responsible.

Contains 25 mg iron

WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

Contains 5,000 mcg biotin

High supplemental biotin may interfere with certain laboratory tests. Tell your healthcare provider and laboratory personnel that you take biotin before testing.

Professional review may be appropriate

Consult a qualified healthcare professional if pregnant or nursing, planning surgery, managing a medical condition (including liver, thyroid, bleeding or neurologic conditions), or taking prescription medication. Do not combine with other iron products unless a professional confirms the need.

Designed for adults. Nutritional and cosmetic support only; not a treatment for a medical cause of hair change. Published studies evaluate named ingredients, not the complete FLOTE RADIANCE Oral Blend. Individual results vary.

Convinced by the science?
Start with the Oral Blend. Three capsules once daily with a meal and water. 90 capsules, a 30-day supply. Liquid Halo™ follows as the outside-in step.